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Segretario Agatha Cirelli. le Foro Boario - 47100 Forli' (FC) Tel. 0543798954 - Fax 05431991112. Presidente Facebook rincon vallegrandinos Calzolari. Vice Presidente Daniele Zagnoli - Massimo Zampieri. Segretario Marika Tumedei.

1679. PubMed PMID: 19043418; PubMed Central PMCID: PMC2605166. Larkin JChiarion-Sileni VGonzalez RGrob JJCowey CLLao CDet al. Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma. The New England Journal of Medicine (2015) ;373: (1):23‚34. doi: 10. 1056NEJMoa1504030. PubMed PMID: 26027431. Hammers HJPlimack ERInfante JRErnstoff MSRini BIMcDermott DFet al. Phase I study of nivolumab in combination with ipilimumab in metastatic renal cell carcinoma (mRCC) [2014 ASCO Annual Meeting, meeting abstract 4504].

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Despite being located in the tropics, and due to its high altitude, because of its tropical location, there are only two seasons in the city, the wet and dry seasons that alternate throughout the year with each lasting about three months. Manizales receives about 1,500 millimetres of precipitation a year and its core economy has traditionally been the cultivation and production of coffee. These companies manufacture products such as liquor, shoes, rubber, chocolate, banks, detergents and soaps, threshing and packaged coffee, software and metallurgy, among others. During the latter half of the century many universities were founded in the city to the point that some studies regard Manizales as the second largest University city in the country. The universities are attended by students from regions of the country such as Tolima, Risaralda, Valle, Quindio, Antioquia, Nari√o.

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