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Tra le sue registrazioni pi√ recenti, l‚integrale pianistica di Emmanuel Chabrier.

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BCG failure is defined as patients with recurrent or persistent disease following the first induction therapy. BCG unresponsive is defined as patients who recur after a minimum treatment of induction plus one course of maintenance therapy or patients who never achieve a CR within 6 months of the last BCG treatment. Patients who recur with T1HG after induction only are also considered unresponsive. The standard of care for these patients is radical cystectomy and so there is a large unmet need for drug development in this space. Valrubicin is the only approved drug for patients with CIS who are BCG-refractory and refuse or are determined to be too high a medical risk for cystectomy. The future is bright however, as there is intense interest from a broad array of pharmaceutical companies and there are novel drug delivery systems being deployed as well (Tables 2, 3).